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Avhandlingar / Theses

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  • Primary hyperparathyroidism : comorbidity and outcome after parathyroid adenomectomy
    Norenstedt, Sophie (Inst för molekylär medicin och kirurgi / Dept of Molecular Medicine and Surgery, 2013-05-20)
    Primary hyperparathyroidism (pHPT) is associated with increased mortality in certain malignant tumours. Breast cancer is the most common and a shared aetiology has been suggested. In a register-based nested case-control ...
  • Selenium cytotoxicity in cancer
    Wallenberg, Marita (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2013-05-20)
    Selenium is an essential trace element, present in the 21st amino acid selenocysteine, which is specifically incorporated into selenoproteins. Today, there are 25 identified selenoproteins in humans, whereof many comprises ...
  • Characterization of the PGE2 pathway in arthritis and inflammation : mPGES-1 as a therapeutic target
    Leclerc, Patrick (Inst för medicin, Solna / Dept of Medicine, Solna, 2013-05-20)
    The inducible prostaglandin (PG) E2 pathway is defined by the concerted activities of the enzymes cyclooxygenase (COX)-2 and microsomal prostaglandin E synthase (mPGES)-1 in producing PGE2. PGE2 has pro-inflammatory and ...
  • Assays for monitoring HIV therapy in low-middle income countries
    Agneskog, Eva (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2013-05-20)
    The purpose of this thesis was to develop and/or evaluate assays for HIV viral load (VL) monitoring and HIV drug resistance testing of potential importance for research studies and clinical care in low- and middle income ...
  • Eclogical impact of antibiotic treatment on human normal microflora
    Rashid, Mamun-Ur (Inst för laboratoriemedicin / Dept of Laboratory Medicine, 2013-05-20)
    The skin and the mucosal surfaces of humans are colonized with microorganisms which are often referred as the normal microflora. There is a biological balance between the human host and the normal microflora in health. ...