Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience: Recent submissions
Now showing items 21-40 of 773
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The adolescent drinker : correlates and predictors of alcohol consumption among Swedish youth
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-11-06)Background: Drinking among adolescents has declined in most high-income countries during the past two decades. In Sweden, the reduction in youth drinking has been more pronounced than in many other parts of the world. The ... -
Treatment of alcohol dependence in primary care
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-10-12)Alcohol dependence is a common disorder and contributes to substantial morbidity and mortality globally. Only 10-20 percent engage in treatment, which makes alcohol dependence the mental disorder with the largest treatment ... -
Nonsuicidal self-injury in adolescence : attempts to improve and develop treatment
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-10-05)Nonsuicidal self-injury (NSSI) and NSSI disorder are common in adolescence and associated with adverse outcomes, including suicide attempts. Detecting vulnerable children and adolescents is essential to decrease the risk ... -
Controlled drinking : a viable treatment goal in alcohol use disorder?
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-25)Alcohol use disorders (AUD) has one of the largest treatment gaps among psychiatric diagnoses, with a treatment coverage of 10 to 20 %. One of the key contributing factors is the lack of treatments aiming for controlled ... -
Dual-energy imaging in stroke : feasibility of dual-layer detector cone-beam computed tomography
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-22)Background: Dual-energy computed tomography (DECT) is increasingly available and used in the standard diagnostic setting of ischemic stroke patients. For stroke patients with suspected large vessel occlusion, cone-beam ... -
Digital interventions to improve mental health and lifestyle behaviors for primary care patients
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-20)Background: Common mental health problems (CMHPs) give rise to large costs and much unnecessary suffering. Most patients with these problems are found in primary care. Positive effects of psychological treatment are well ... -
Inflammatory events and their effect on neural stem cell differentiation
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-09-08)Inflammation plays a dual role in the central nervous system (CNS), serving as a defence mechanism to protect and restore neural tissue following injuries or infections, but also driving degeneration and aggravating damage. ... -
Genetic, magnetic resonance imaging and body fluid biomarker associations with severity of multiple sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-08-29)Multiple sclerosis is a chronic and progressive neuroinflammatory disease that leads to demyelination and neurodegeneration in the central nervous system (CNS). Previous research has identified a wide range of environmental, ... -
Supporting the supportive parents : community reinforcement and family training for families affected by alcohol or substance use
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-08-18)Background: Concerned significant others (CSOs) of individuals with problematic alcohol- or substance use show increased levels of psychiatric and somatic ill-health, social and economic problems and exposure to violence. ... -
Minimally invasive catheter-based technologies
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-08-10)A simple incision procedure in a blood vessel makes the entire vascular system accessible. Through contrast injection and X-ray visualization, the vascular tree can be mapped and navigated through manual manipulation of ... -
Activity restrictions, treatment and work disability among people with multiple sclerosis
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-07-28)Background: Multiple sclerosis (MS) is a disease that commonly occurs among individuals of working age. Its symptoms are heterogeneous and affect people with MS (PwMS) considerably in different aspects of their lives. ... -
From efficacy to implementation : applying internet-delivered cognitive behavioural therapy in the treatment of OCD
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-06-29)Background: Obsessive Compulsive Disorder (OCD) and Body Dysmorphic Disorder (BDD) are closely related psychiatric conditions associated with functional impairment across various life domains, an increased risk of suicide, ... -
The pill and the will : pharmacological and psychological modulation of cognitive and affective processes
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-22)Background: Impairments in cognition are components of practically all psychiatric disorders and in that sense transdiagnostic factors. In both clinical and non-clinical populations, ‘hot’ and ‘cold’ cognitive control, ... -
Cannabis use in adolescence : studies of trends, correlates and adverse mental health consequences
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-11)Background: Cannabis is currently the most commonly used illicit psychoactive substance. Cannabis use is typically initiated during adolescence and is more common among young people than among adults. Cannabis use is ... -
Brain imaging of chronic pain : from the association with immune mechanisms to brain networks
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-10)Musculoskeletal chronic pain encompasses the two mechanistically distinct categories of nociplastic pain and nociceptive pain. The former is classically typified by fibromyalgia whereas the latter is characteristic of ... -
Obsessive-compulsive disorder : novel insights on executive functions, gut microbiome, and genetics
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-10)Background: Obsessive-compulsive disorder (OCD) is characterized by intrusive thoughts and images, and repetitive, time-consuming compulsions. It causes disability and impaired quality of life. The neurobiological model ... -
Sickness absence and disability pension among injured bicyclists and pedestrians
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-04)Background: Active transportation such as walking and bicycling provides an opportunity for individuals to incorporate physical activity into daily life. It has a positive impact on public health and is an important aspect ... -
Alcohol-related harm among youth in Sweden
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-05-02)Background: Compared to before the turn of the millennium, adolescents are now less likely to drink alcohol and to engage in heavy episodic drinking, both in Sweden and in many other countries. However, in societies where ... -
Deciphering and fine-tuning of myeloid cells in CNS demyelinating conditions
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-04-21)Demyelination in the central nervous system (CNS) is a characteristic of various neurological disorders, such as multiple sclerosis (MS), neuromyelitis optica (NMO), subacute combined degeneration (SCD), tabes dorsalis ... -
Malpositioned and dislocated intraocular lenses : management, complications and surgical repositioning
(Inst för klinisk neurovetenskap / Dept of Clinical Neuroscience, 2023-04-06)Cataract surgery (exchange of the non-transparent crystalline lens with an IOL) is the most frequent surgery in Sweden, accounting for more than 130000 surgeries per year. Therefore, complications associated with cataract ...